Aluminum does not make a very good bearing surface. If your parts are going to slide relative to one another, you should consider using plastic or steel.
Aluminum is stiff and lightweight. Use it for cantilevered arms or other objects. If it is absolutely necessary, aluminum can be made thin and yet still quite strong, so if holes need to be made close to an edge, aluminum is a good choice. It is also a good choice for small delicate parts.
Aluminum is an excellent electrical conductor. Be careful not to short out any electrical wires by touching bare aluminum.
To modify, you can use the following tools: Bandsaw, Sander, Die, Lathe, Mill
You should not use: Brake, Punch, Shear, Roller, Grinder.